Cetirizine, a human metabolite of hydroxyzine, is a potent and selective antagonist of peripheral H1-receptors. In vitro receptor binding studies have shown no measurable affinity for receptors other than H1-receptors.
Ambroxol is the active metabolite of bromhexine. Ambroxol causes an increase in secretion in the respiratory tract. It promotes surfactant production and stimulates ciliary activity. These effects assist the flow of mucus and its removal (mucociliary clearance). An improvement in mucociliary clearance was demonstrated in clinical pharmacological studies. The increase in secretion and mucociliary clearance facilitate expectoration and reduce the cough.
Each uncoated tablet contains:
Ambroxol Hydrochloride BP 30 mg
Cetirizine Hydrochloride BP 5 mg
Excipients: Lactose BP, Starch BP, Microcrystalline Cellulose BP, Methyl Hydroxybenzoate BP, Propyl Hydroxybenzoate BP, Purified water BP, Magnesium Stearate BP, Purified Talc BP, Colloidal Anhydrous Silica BP, Sodium Lauryl Sulfate BP.
Respiratory tract diseases with discharge of viscous mucus:
Oral use, with meals and drinking a small amount of liquid.
Adults and adolescents over 12 years: 1 tablet 2 times a day.
Children aged 6 to 12 years: ½ tablet 2 times a day.
Not recommended for use without a doctor’s prescription for more than 4-5 days.
During treatment, need to drink plenty of fluids (juice, tea, water), as it increases the mucolytic effect of the drug.
